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From First Principles
Krishna Choudhary and Lester Nare
From First Principles is a fast, funny, and rigorous breakdown of the biggest science stories of the week, hosted by Lester Nare and physicist Krishna Choudhary, PhD. We go past headlines into the actual mechanics: what happened, why it matters, and what everyone’s missing. Expect physics, space, AI, energy, biotech,…
54 episodes tracked Similar shows

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How Quantum Computing Actually Works (Part 1) (EP 54)
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2h 11m ·

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What Claude Actually Did to the Riemann Hypothesis (EP 53)
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1h 47m ·

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The Amazon’s Hidden Civilization (One Year Anniversary) (EP 52)
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The Tech Elon Has Been Waiting For (EP 51)
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1h 44m ·

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AI Breaks a 90-Year Math Problem, Life’s Alphabet in Space, and Science Funding (EP 50)
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FIFA Data Scientists Explain Match Momentum (EP 49)
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Black Hole Movies, Digital Heart Twins, and World Cup Tech (EP 48)
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1h 48m ·

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America 250: The Breakthroughs That Built American Science — Part 2 (EP 47)
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2h 21m ·

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America 250: The Breakthroughs That Built American Science — Part 1 (EP 46)
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1h 50m ·

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The Physics of the World Cup: VAR, Smart Balls, and Soccer Aerodynamics (EP 45)
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New Rules For Heredity (Non-Mendelian Inheritance of Epigenetics) (EP 44)
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1h 37m ·

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Dr. Michael Blanton on Open Data, Galaxy Surveys, and the Future of Astronomy (EP 43)
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How Scientists Actually Study Dark Matter (EP 42)
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1h 06m ·

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Dr. John Mulchaey on Carnegie Science and the Future of Astronomy (EP 41)
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37m ·

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Ant Scans, Lunar Chickpeas, Hidden Galaxies & Superconductivity (EP 40)
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The Prometheus Constellation: Dramaturgical and Scientific Analysis of the Physicists in Oppenheimer (EP 39)
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1h 37m ·

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Harder Than Diamond? The New Hexagonal Diamond Breakthrough (EP 38)
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Artemis II: Deep Dive on the Moon Flyby, Earthset, and Reentry (EP 37)
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1h 25m ·

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Artemis II, Claude Code Leak, iPhone Spyware & Project Hail Mary (EP 36)
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Can AI Help Wake Coma Patients? The Science of Consciousness (EP 35)
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1h 08m ·

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AI Cancer Vaccines, Strange Fish, Ketamine, and Ancient Life (EP. 34)
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44m ·

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Can Human Neurons Really Play Doom? The Science Behind Wetware (EP. 33)
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5,000-Year-Old Bacteria, Solar Storms, Dogs, and Meta’s AI War (EP. 32)
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Optovolution: Teaching Proteins to Think Like Computers (EP. 31)
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Can We Stop an Asteroid? The Physics Behind NASA’s DART Mission (EP. 30)
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Astrobiology’s Biggest Survival Test + A Vaccine Against Everything? (EP. 29)
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Dark Galaxies, Fuzzy Dark Matter, and an Alzheimer’s Breakthrough (EP. 28)
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1h 51m ·

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Dream Engineering, the Proton Radius Puzzle, and an ALS Breakthrough (EP. 27)
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2h 12m ·

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Winter Olympics Deep Dive: Ice Physics, Performance Pressure, and Climate Change (EP. 26)
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Plants, Quantum Sensors, and Predicting Cancer Evolution (EP. 25)
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1h 49m ·

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Artemis II, Apollo, and the Physics of Going Back to the Moon (EP. 24)
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1h 09m ·

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JWST’s “Little Red Dots,” TimeVaults, and the Dawn of Math (EP. 23)
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1h 40m ·

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Cloud9 Dark Matter Halo, Jellyfish Sleep, and String Theory Hidden in Nature (EP. 22)
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1h 39m ·

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Roman Concrete, Brain “Cognitive Legos,” DeepSeek, and Econophysics (EP. 21)
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1h 58m ·

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The Physics Behind Fusion’s Biggest Problem (Season Finale) (EP. 20)
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1h 17m ·

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The Race to the Double Helix — Watson, Crick, Franklin & the Real Story of DNA (EP. 19)
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1h 34m ·

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3I/ATLAS Explained, Forensic Fingerprints & Alzheimer’s Breakthrough (EP. 18)
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1h 27m ·

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Hypersonic Physics, Deep Sea Life & Princeton’s Millisecond Qubits (EP. 17)
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1h 32m ·

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Octopus Camouflage, Orcas vs. Sharks, Civet Coffee & Sub-Diffraction Telescope Tech (EP. 16)
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1h 17m ·

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AI-Generated Genomes, Retinal Implants, and Palomar’s Mystery Lights Explained (EP. 15)
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2h 03m ·

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Chen Ning Yang — The Man Who Unlocked Symmetry (EP. 14)
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1h 43m ·

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Portable Muon Beams, Sodium Batteries, and the Secret to Long Life (EP. 13)
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1h 36m ·

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From Princeton to the Nobel Prizes — How FFP Started + 2025 Nobel Recap (EP. 12)
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1h 12m ·

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From Cells to Circuits to Crystals — 2025 Nobel Prizes Unpacked (EP. 11)
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1h 54m ·

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AI Supercharges CRISPR & LIGO (Nobel Prize Week Preview) (EP. 10)
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2h 36m ·

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China’s AI Breakthrough, Time Crystals, Hidden Viruses, & Brightest Cosmic Signal (EP. 9)
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1h 41m ·

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Strongest Evidence for Alien Life? (Mars, K2-18b & JWST) (EP. 8)
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1h 19m ·

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Interstellar Visitor 3I/Atlas, Human Longevity Plateau, New No-Sort Plastic & Analog AI (EP. 7)
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1h 23m ·

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New Supernova, Virus+Bacteria vs Cancer, Electron Spin, Bee Superfood (EP. 6)
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1h 28m ·

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Hacking The Human Brain, Unlocking Our DNA, Unbreakable Diamonds & The Quantum Magician (EP. 5)
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2h 09m ·

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3rd Interstellar Visitor, Rubin’s Sky Camera, AI CRISPR Boost & T. rex Blood Vessels (EP. 4)
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1h 22m ·

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Oldest Molecule, Programmable Proteins, Europa Radar & Light’s Double Life (EP. 3)
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1h 16m ·

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Hidden Star in Betelgeuse, Dancing Atoms, Ultra-High-Energy Cosmic Rays & VR Immunity (EP. 2)
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1h 17m ·

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Earth’s 1-ms Day, Baby Solar Systems, Record Black Hole Crash, CRISPR Cancer Hack & AI Indiana Jones (EP. 1)
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55m ·
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